Similar to the original Binding of Isaac, the plot is based on the biblical story of the same name and was inspired by McMillen's religious upbringing. The third and final expansion, Repentance, was released in March 2021. Afterbirth and Afterbirth+, in October 2015 and January 2017, respectively, with more game content and gameplay modes Afterbirth+ also added support for user-created content. This platform had limitations and led McMillen to work with Nicalis to produce Rebirth with a more advanced game engine, which in turn enabled the substantial addition of new content and gameplay features. Rebirth is a remake of The Binding of Isaac, which was developed by McMillen and Florian Himsl and released in 2011 as an Adobe Flash application. The PlayStation 5 and Xbox Series X/S versions were released in November 2021. Rebirth was released for Linux, Microsoft Windows, OS X, PlayStation 4 and PlayStation Vita in November 2014, for Xbox One, New Nintendo 3DS and Wii U in July 2015, for iOS in January 2017 and for Nintendo Switch in March 2017. To uninstall and restore the pills, simply delete the extracted file.The Binding of Isaac: Rebirth is an indie roguelike video game designed by Edmund McMillen and developed and published by Nicalis. Extract the contents of version you want into The Binding of Isaac Rebirth/resources.
Apologies for the lack of good screenshots - I'm not sure how to picture things not being there?
See their mod here that removes only the Retro Vision Pill. Thanks to Wofsauge, who worked out the method to remove pills. PHD is all but useless, but it's not like you need it now.
Note that this removes Full Health as its own pill, but you can still get it by being at low health with Bad Trip. You're likely to get a lot of stat downs with this, and PHD is at its strongest here. This reduces the selection to fourteen, meaning all but one pill will be in play in each run. This includes every pill that doesn't have a good or bad equivalent, both potentially negative, like Hematemesis, or objectively positive, like 48 Hour Energy.